Search results for "causal mediation"

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Birth weight, adult weight, and cardiovascular biomarkers : Evidence from the Cardiovascular Young Finns Study

2021

This study quantifies the causal effect of birth weight on cardiovascular biomarkers in adulthood using the Cardiovascular Risk in Young Finns Study (YFS). We apply a multivariable Mendelian randomization (MVMR) method that provides a novel approach to improve inference in causal analysis based on a mediation framework. The results show that birth weight is linked to triglyceride levels (β = −0.294; 95% CI [−0.591, 0.003]) but not to low-density lipoprotein (LDL) cholesterol levels (β = 0.007; 95% CI [−0.168, 0.183]). The total effect of birth weight on triglyceride levels is partly offset by a mediation pathway linking birth weight to adult BMI (β = 0.111; 95% CI [−0.013, 0.234]). The nega…

adult BMIbirth weighttriglyseriditbiomarkkerit3121 Internal medicine3142 Public health care science environmental and occupational healthmonimuuttujamenetelmätLDL cholesterolkausaliteettisydän- ja verisuonitauditsyntymäpainomultivariable Mendelian randomizationLDL-kolesteroli3111 Biomedicinepainoindeksigeneettiset tekijättriglyceridescausal mediation
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Does self-efficacy influence academic results? A separable-effect mediation analysis

2021

In causal mediation analysis, natural effects are identified only under strict assumptions involving cross-world counterfactuals. An alternative approach recently developed, called separable, allows for identification of mediational effects in a wide range of models, since it relies on weaker assumptions than those required by natural effects. In this paper, the separable-effect approach is revised and an application to data is presented.

causal mediation analysis separable effects iSP studySettore SECS-S/01 - Statistica
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